Maven Bioscience Launches KindRx, a Revolutionary Pet and Veterinary Product Line

June 2024 Maven Bioscience has announced the launch of KindRx, a new division dedicated to creating cutting-edge pet and veterinary products. After years of working behind the scenes producing white-label pet products, the company is now making its mark on the global market with the introduction of the world’s most advanced line of pet and veterinary solutions.

KindRx products are designed for both everyday pet owners and veterinary professionals, offering a range of innovative formulations aimed at improving animal health and wellness. With this global launch, Maven Bioscience is positioning KindRx as a leader in the field, providing high-quality, science-backed solutions for pets.

“KindRx represents the culmination of years of research and development,” said a Maven Bioscience spokesperson. “We’re proud to bring our expertise from the pharmaceutical and precision medicine fields into the pet care industry, delivering products that will set a new standard for pet wellness.”

With this bold move, Maven Bioscience aims to transform the pet care landscape by offering specialized products that blend scientific precision with practical, user-friendly applications for both pet owners and veterinary experts.

Maven Hemp Rebrands as Maven Bioscience, Signaling Shift to Precision Medicine

February 2024 Maven Hemp, a leading player in the CBD industry, has officially rebranded as Maven Bioscience, marking its expanded focus into the field of pharmaceutical medicine and clinical testing. The company, previously known for its hemp-derived products, is now positioning itself as a global leader in precision medicine.

“We are not just a CBD company,” CEO and Founder, Zev Barnett explained. “We have worked, and continue to work, with top doctors and researchers from around the world to develop the best products for you.”

The name change reflects Maven Bioscience’s growing involvement in personalized healthcare. The company is pioneering products tailored to individual DNA profiles- with their groundbreaking DNA-matched formulas. These personalized treatments utilize data from either  Endo-DNA genetic testing kits or customers’ existing genetic data from popular services such as 23andMe or AncestryDNA.

By analyzing an individual’s unique genetic profile, Maven Bioscience aims to offer more effective, personalized treatments that deliver optimal results. The move signals the company’s commitment to innovation in the burgeoning field of precision medicine, ensuring that their products meet the needs of consumers in the most targeted way possible.

With this shift, Maven Bioscience is carving out a distinctive niche in the healthcare landscape, blending the power of genetics with pharmaceutical expertise.

4th Cannamerica Event in Quito, Ecuador 2023

Event Name: 4th Cannamerica Event in Quito, Ecuador 2023
Date: Feb 9-11 2023

Maven is proud to be the Cannabis Cotopaxi Sponsor of the 4th Cannamerica Event in Quito, Ecuador, Feb 9-11 2023

Cannamerica is featuring “Cannabis from multiple and new perspectives” including Master Lectures and Scientific Work from over 30 international expert speakers on phytocannabinoids

Maven Hemp’s CEO, Zev Barnett, will join over 30 other international speakers presenting talks sharing their insights and he will be focusing on how innovation is changing cannabis science in the animal and pet care industries.

LATAM Conference in Panama 2022

Event Name: LATAM Conference in Panama 2022
Date: September 1 & 2, 2022

Maven Hemp is proud to be a gold sponsor for the 2022 LATAM CANN BIZ conference in Panama City, Panama.

LATAM CANN BIZ is an interdisciplinary conference focusing on global and regional industry trends and up-to-date information on emerging regulatory frameworks, technology, science, and best agricultural and production practices in the cannabis industry.

Maven Hemp’s CEO, Zev Barnett, will join over 40 other international speakers presenting talks sharing their insights and focusing on how to be successful in the cannabis industry.

Holistic Virtual Physical Therapy Program Partnership

Maven Hemp, a Denver, Colorado based premiere CBD and Cannabinoid product manufacturer with a mission to change the face of medicine is proud to announce a partnership that takes another step in making their mission a reality for people around the world.

Maven has partnered with Denver-based Symfit Physical Therapy & Fitness, who specializes in video-on-demand (VOD) and virtual physical therapy options and is the winner of WebPT’s 2020 award for the most innovative physical therapy practice at their annual Ascend conference.

Maven and Symfit together have launched a virtual physical therapy program that combines healthy posture and sleep strategies along with mindfulness exercise with Maven’s cannabinoid-based products to help people fix themselves that can be done in the privacy of their own home, office, or anywhere.

Programs for a healthy neck, shoulders, lower back, hips, and knees are all offered.

“With this partnership, we have the opportunity to provide patients best-in-class care along with premium grade CBD and Cannabinoid-based products in the comfort of their own home at a cost that is typically less than out-of-pocket insurance. It is truly a step forward in changing medicine and we’re grateful to be leading the charge in this initiative” says Maven Hemp CEO Zev Barnett.

Personalized Cannabis is a thing? YES!

Are you an ultra-metabolizer of CBD but an intermediate metabolizer of THC?

Back in the “old days”, cannabis dosage was left to trial and error by the user. Lots and lots of experimentation with varying degrees of success. As even the most casual user of cannabis products knows, every person is different when it comes to tolerance levels and what works best for their particular situation.

The advancement of cannabis science has come a long way, and now anyone can benefit from the healing powers of “personalized cannabis” with a DNA test from EndoDNA, the most comprehensive endocannabinoid DNA test available today.

Len May, CEO and Co-founder of Endo-Canna Health (parent company of EndoDNA) and author of the book Making Cannabis Personal sat down on the podcast BUDDING INTERESTS and spoke with host Zev Barnett (available here: https://tinyurl.com/LenMay ) and gave the lowdown on this game changing innovation in the cannabis-as-medicine movement.

 

All a person has to do is go to EndoDNA.com and either order one of their EndoDNA kits or upload their raw digital DNA report from 23 and Me or Ancestry.com to get a free immune function Genetics report.

The EndoDNA test analyzes more than 600,000 SNPs (Single Nucleotide Polymorphisms, pronounced “SNIPS”) related to your endocannabinoid system. These specific SNPs exhibit genetic variations which have been shown in academic research to be associated with specific medical conditions, mental wellness and physical health.

Information gleaned from this report is then used to help you optimize your cannabinoid and CBD experience in a number of ways, including:

  • Learn the most ideal ratios, methods and dosing for your body.
  • Know which terpenes and cannabinoids to see out and which to avoid.
  • Understand any risks or benefits from using cannabinoids for your specific genotype.
  • Identify the specific cannabinoid formulations most aligned with your genetics.

EndoDNA then will make formulation suggestions for your specific genetics as well as provide a product marketplace where you can find Endo-Aligned Trusted formulations and a product geolocator to help you find those products in your area.

Tune into BUDDING INTERESTS to learn more about EndoDNA and how to personalize your cannabis consumption. All BUDDING INTERESTS listeners get 25% off both the full EndoDNA test and raw data uploads. See the podcast description for the discount code.

Radicle Science Launches Study to Determine Effectiveness of CBD Products

Featuring Parker, Colorado-based CBD company Maven Hemp

The 3,000 participant study will capture and publish the most comprehensive data ever collected on CBD product effectiveness from 13 commercially available U.S. brands, including Maven Hemp.

Radicle Science, a transformative healthtech B-corp validating natural products for the first time, announces the launch of the Radicle ACES (Advancing CBD Education and Science) study.

Using a virtual, direct to consumer (D2C) approach, Radicle ACES is the largest and most comprehensive randomized controlled trial (RCT) of its kind, collecting data on thirteen mission-driven U.S. CBD brands, featuring Maven Hemp alongside ALTWELL, Charlotte’s Web, Columbia Care, Healer, Lord Jones, MD FARMA, Peels (a citrus-derived brand), Prospect Farms, PURAURA Naturals from Enhanced Botanicals, Rae Wellness, Trokie, and Verséa Wellness.

“We believe in the importance of having access to verified data that supports the ways our company makes a positive impact. Participating in the Radicle ACES study allows us to align with Radicle, a B-Corp that shares our values, while building trust and confidence as we work to distribute our products to doctors and patients across The Americas and beyond. We’re also in the process of B-Corp certification, and are making progress towards our impact goals every day. We’re proud to align with mission-driven partners, including Radicle Science and the other 12 brands in the Radicle ACES study.” – Zev Barnett, Founder and CEO of Maven Hemp

Radicle ACES is Institutional Review Board (IRB) approved and will capture CBD effectiveness data directly from 3,000 study participants. During the four-week study, participants will use the Radicle Science platform to track consumption and effectiveness of orally ingested CBD products on well-being, quality of life, pain, sleep disturbance, and anxiety.

Radicle ACES will use validated, standardized health indices to gather health outcome data from a diverse population across a variety of ethnicities, age groups, geographies, behavioral habits, and pre-existing health conditions.

“We’re applying science to understand the effectiveness of CBD products used by tens of millions of Americans every day,” said Jeff Chen, MD/MBA, Co-founder and CEO of Radicle Science.

Academic collaborators include Miroslav Backonja, MD (Clinical Professor, University of
Washington), Chris Colwell, PhD (Professor, UCLA), Derek Loewy, PhD (Director of Behavioral Sleep Medicine at Scripps Clinic Sleep Center), Ethan Russo, MD (Founder and CEO of CReDO Science), Kate Taylor, PhD (Associate Professor, UCLA), Jill Waalen, MD/MPH (Co-Director of Biostatistics at Scripps Research), and more.

The Real World Evidence (RWE) collected will inform scientific understanding on dosing, usage patterns, user characteristics, effectiveness across conditions, and predictors and modifiers of treatment response.

“The Radicle ACES study aims to answer lingering questions as to who should take cannabidiol, how much and for what conditions, as well as differing dosage patterns,” said Ethan Russo, MD, Scientific Expert for Radicle Science, and Founder and CEO of CReDO Science. “CBD is much more subtle in its effects and quite benign compared to THC. Patients are unclear on what product to choose and healthcare providers don’t yet have the data to counsel on proper dosage.”

For Maven Hemp, sharing data and answers from the Radicle ACES study will solidify the company’s ability to create positive impact across the local Colorado hemp production and consumption ecosystem. Alongside the company’s physician partners across the globe, as a custom product manufacturer, Maven Hemp aims to support the realization of improved patient outcomes.

Anonymized aggregate results will be released in October 2021. For more background on Radicle ACES methodology and additional insights from collaborators and experts involved in the study, see these Radicle Resources articles.

Follow Maven Hemp on LinkedIn and Instagram to stay updated on the Radicle ACES study as well as new product offerings. Visit the Maven Hemp website to browse through current products and engage with the company’s efforts to realize positive economic, social and environmental impact locally and internationally.

The Difference between CBD Isolate, THC-Free and Full Spectrum Products

Differences in Cannabis Oil Products

Cannabidiol is one of hundreds of chemicals produced by the cannabis plant. Together, these groups of chemicals are called cannabinoids (or phytocannabinoids if you want to be specific about the fact that they are from a plant). These are usually extracted as something called cannabis oil (oftentimes misspelled as “canibus oil” or “cannabus oil”). Products made from this oil often have different labels based on the purity of the extract, and the level of THC content. In this article, we’ll take a look at some of the most common hemp extract labels that you’ll run into when purchasing CBD hemp oil.

CBD Isolate

While it does take more work, CBD can be isolated from the extract and this is labeled as “CBD Isolate” or “Isolate CBD”. These kinds of products don’t contain any other cannabinoids, terpenes, flavonoids, and other plant chemicals. This is achieved by a stringent purification process that begins by extracting the oil from high-CBD hemp plants. From there, the oil is refined to remove contaminants, then distilled to concentrate the CBD to approximately 80%. Chromatography purifies the CBD from the distillate and then that substance is crystallized to yield a 99% pure CBD powder.

When shopping for CD isolates, it’s a good idea to make sure that the product has been tested by a third-party lab to ensure purity. Maven Hemp CBD isolate is tested and retested throughout the process to ensure purity.

Zero-THC Oil

A zero-THC label means that the hemp extract contains the full spectrum of the plant including the other phytocannabinoids but doesn’t contain any THC. THC stands for tetrahydrocannabinol and is the only psychoactive cannabinoid. Cannabidiol and the other chemicals do not. For people who want the benefits of a broader spectrum of the cannabis plant, opting for a zero-THC product may be the way to go, in comparison to the CBD isolate.

Full-Spectrum CBD

When it comes to full-spectrum products, it’s important to remember that the legal hemp plant still contains 0.3% THC or less. Since plants are living organisms, it’s difficult to predict the exact amount of THC a hemp plant will produce. [1] BeyondTHC, the hemp plant contains hundreds of other compounds, such as terpenes, flavonoids, lipids, omega 3 acids, and omega 6 acids, which are beneficial for anti-inflammatory effects. Ingesting the full spectrum of the hemp plant is the optimal way to support the endocannabinoid system.

Is 0.3% THC a lot?

Hemp products have less than .3% THC. A typical dispensary product could have 15%-100% more THC. Important to read labels to not be misled.

Delivery Method of CBD

Finally, the delivery method that you choose to use will affect how much time it takes before you feel the effects. Using an inhaler is the fastest method because the CBD is directly absorbed into your bloodstream through your lungs. Eating or using a tincture takes longer because your mouth and gastrointestinal tract must first absorb the CBD. And remember, CBD loves oils and hates water, so it’s a good idea to eat or use CBD oils with other oily/high-fat foods such as avocados, milk, or ice cream.

Always Check the Label!

Next time you’re out shopping for CBD products, remember to check the label for what kind of hemp extract it contains. Also make sure to check to see if the product has been tested, verified, and certified by a third-party testing lab. To get the best experience from using CBD, it’s important that high-quality products are used.

At Maven, we curate only the highest-quality raw materials in America to create our CBD products. You can also be confident that our products are pure and contain what they say they contain. How? Because every single product we provide is Lab-Tested by an independent third-party lab and produced using Good Manufacturing Practices (GMP).

References

  1. Jikomes, N., & Zoorob, M. (2018). The Cannabinoid Content of Legal Cannabis in Washington State Varies Systematically Across Testing Facilities and Popular Consumer Products. Scientific reports, 8(1), 4519. doi:10.1038/s41598-018-22755-2

 

 

How do I Know CBD Oil is Safe?

CBD Compared to Other Drugs

There are many illegal drugs out there that can cause you harm if ingested in high doses. There are even legal, every day, food-borne drugs that must be consumed in moderation. Things like alcohol or nicotine can be lethal at high doses. Even caffeine can kill you if you drink too much of it. Cannabis oil, specifically CBD hemp oil, is actually much safer. In this article, we’ll talk about some of the reasons why.

CBD is Not Intoxicating

A group of doctors at the Mayo Clinic recently released a review of all the papers on the National Institute of Health regarding CBD oil. [1] The conclusion that they came to was that CBD and other hemp extracts were nonintoxicating and could have many potential uses in medicine. This review also looked at any adverse effects CBD might have on people.

Most Individuals can Tolerate Large Doses of CBD

Turns out, there were studies where people took high doses (300mg/day) for up to 6 months and were fine. Another showed that a group of patients took 4 to 5 times that dosage for 4 weeks and didn’t experience any bad side effects. With CBD, more is not always “more effective” with most people needing far less than any “maximum dose.” In fact, some recent data that we’ve collected, in concert with GoFire, reveals that consumers of Maven Hemp products find that maximum effectiveness is found in very moderate doses.

Favorably safe

One of the most attractive qualities of CBD is that even if you do experience side effects, they’re extremely mild compared to side effects from other drugs. A German study from 2017 found that cannabidiol was “favorably safe” for humans. The side effects included things like diarrhea, tiredness, and changes in appetite. [2] As with any drug, always discuss consuming CBD oil with your doctor if you are taking other drugs.

There was only one study where severe side effects were experienced, but even then, it was amongst psychiatric patients who were most likely taking other medication. Out of the 1600+ patients using CBD, only one person experienced severe side effects (muscle seizures and/or spasms). [3] Yes, you read that right, one out of over 1600+ patients.

CBD and Elevated Liver Function

A somewhat concerning observation came from some of these studies, though. Many of the patients had elevated liver function. This means that the liver is working overtime for some reason. Even the FDA suggests that patients get a liver function test before starting on the FDA-approved CBD drug, Epidiolex. [4]

Beware of Synthetic Cannabinoids

Based on these studies, natural CBD oil from the hemp plant is not harmful to people. However, synthetic cannabinoids have definitely killed people or left some with massive organ damage. [5] These synthetic chemicals have sketchy origins and are often laced with other things such as anticoagulants (these are chemicals that thin your blood and cause uncontrolled bleeding). [6]

The moral of the story is to make sure that you only purchase natural CBD oils. Always read the labels, ask questions, and check that the product has passed the Good Manufacturing Practice test. At Maven, all of our CBD products are tested for purity by independent third-party labs so you know what you’re putting in your body is the best quality, natural CBD in the country.

References

  1. Vandolah, H. J., Bauer, B. A., & Mauck, K. F. (2019). Clinicians’ Guide to Cannabidiol and Hemp Oils. Mayo Clinic Proceedings, 94(9), 1840–1851. doi: 10.1016/j.mayocp.2019.01.003
  2. Iffland, K., & Grotenhermen, F. (2017). An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies. Cannabis and cannabinoid research, 2(1), 139–154. doi:10.1089/can.2016.0034
  3. Hoch, E., Niemann, D., von Keller, R., Schneider, M., Friemel, C. M., Preuss, U. W., … Pogarell, O. (2019). How effective and safe is medical cannabis as a treatment of mental disorders? A systematic review. European archives of psychiatry and clinical neuroscience, 269(1), 87–105. doi:10.1007/s00406-019-00984-4
  4. Epidiolex [package insert]. Carlsbad, CA: Greenwich Biosciences, Inc; 2018. (US Food and Drug Administration website)https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210365lbl.pdf; 2018. (Published June 2018. Accessed November 16, 2018)
  5. Spice/ K2, Synthetic Marijuana. (n.d.). Retrieved October 7, 2019, from https://www.dea.gov/factsheets/spice-k2-synthetic-marijuana.
  6. National Institute on Drug Abuse. (2018, July 26). FDA Warns of Synthetic Cannabinoids Laced with Anticoagulant. Retrieved October 7, 2019, from https://www.drugabuse.gov/emerging-trends/fda-warns-synthetic-cannabinoids-laced-anticoagulant.

 

What is CBD? How is CBD different from THC?

What is CBD?

CBD stands for cannabidiol. It’s one of the 145+ phytocannabinoids produced by the cannabis plant, Cannabis sativa L, or C. sativa. Humans also produce similar compounds called endocannabinoids. Often, you’ll see people refer to CBD as a cannabinoid or phytocannabinoid. [1]

Emerging CBD Products

In recent years, CBD products have been appearing everywhere. The 2018 Farm Bill clarified the legal status of hemp plants, which are cannabis plants containing less than 0.3% THC. However, the Farm Bill only legalizes hemp on the federal level. [2] Individual states also need to legalize hemp and hemp products, such as CBD, for stores to legally sell it. For those of you living in the 47 CBD-friendly states, you’ve probably seen more and more stores advertising CBD and hemp products from CBD hemp oil and tinctures, to brownies and cookies. Even celebrities have started to endorse this product. But what is CBD exactly?

How is CBD different from THC?

Strangely enough, CBD and THC are very similar molecules. The main difference is that CBD is non-psychoactive. It does not cause changes in mental state when it is ingested. [3] This means that when you ingest products or use a hemp extract, you don’t get a happy, euphoric feeling. However, CBD has been known to provide relief from seizures, pain, and anxiety. There have even been studies on CBD’s effect on different types of cancer cells. [4, 5, 6, 7] Another difference between these two cannabinoids is that CBD seems to take away the anxiety and other unpleasant side effects that people often get when they inhale THC. In a way, they work together, and against each other!

The reason we can feel the effects of CBD is because of our own endocannabinoid system, discovered in the early 1990s by researchers Raphael Mechoulam (currently associated with the Jerusalem’s Center for Research on Pain), William Devane and Dr. Lumir Hanus of the National Institute of Health.

CBD Studies

While scientists have studied THC and cannabinoids as a whole, there’s still very little research on what receptors CBD directly affects. This is not to say that there is no effect, but rather, scientists are trying to pinpoint how CBD interacts with our biological systems. Now that the World Health Organization has sought to remove CBD from the (international) Schedule IV list, roadblocks to determine how CBD may be able to help people across the globe are being removed.

Most studies agree that CBD binds poorly to the known endocannabinoid system receptors, but from there, the mechanisms of CBD remain unclear. [8] There are plenty of anecdotal reports about CBD, but any chemical with potential health benefits must be tested scientifically. With that said, international clinical studies are being run to discover CBD’s effects on a myriad of ailments from anxiety and sleep disorders to epilepsy and cancer.

How Does CBD Work?

The studies on how CBD specifically works in the human body point to its ability to calm down nerve cells. [9] How CBD does this is still unknown, but the theory is that CBD somehow changes the way nerves send signals. [10] It’s important to note that these studies are still in their preliminary stages. The good news is that with the legalization of hemp, scientists in the U.S. can obtain different samples and types of CBD and other cannabinoids. This means more studies on how CBD specifically affects the human body.

Maven Hemp – At the front lines of Cannabis Research

Israel is at the forefront of the research on potential medical uses of CBD and other cannabinoids found in the cannabis plant. Unlike many CBD companies, the Maven Hemp team is spread across Israel and the U.S. and is armed with the most up-to-date research regarding the effects of CBD products. Our CBD oils, tinctures, and isolates are produced in GMP-rated facilities using certified processes, to bring you pure, lab-tested CBD products you can trust.

References

  1. Iffland, K., & Grotenhermen, F. (2017). An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies. Cannabis and cannabinoid research, 2(1), 139–154. doi:10.1089/can.2016.0034
  2. GovTrack.us. (2019). H.R. 2 — 115th Congress: Agriculture Improvement Act of 2018. Retrieved from https://www.govtrack.us/congress/bills/115/hr2
  3. Pellati, F., Borgonetti, V., Brighenti, V., Biagi, M., Benvenuti, S., & Corsi, L. (2018). Cannabis sativa L. and Nonpsychoactive Cannabinoids: Their Chemistry and Role against Oxidative Stress, Inflammation, and Cancer. BioMed research international, 2018, 1691428. doi:10.1155/2018/1691428
  4. Sharafi, G., He, H., & Nikfarjam, M. (2019). Potential Use of Cannabinoids for the Treatment of Pancreatic Cancer. Journal of pancreatic cancer, 5(1), 1–7. doi:10.1089/pancan.2018.0019
  5. Alharris, E., Singh, N. P., Nagarkatti, P. S., & Nagarkatti, M. (2019). Role of miRNA in the regulation of cannabidiol-mediated apoptosis in neuroblastoma cells. Oncotarget, 10(1), 45–59. doi:10.18632/oncotarget.26534
  6. Ivanov, V. N., Wu, J., Wang, T., & Hei, T. K. (2019). Inhibition of ATM kinase upregulates levels of cell death induced by cannabidiol and γ-irradiation in human glioblastoma cells. Oncotarget, 10(8), 825–846. doi:10.18632/oncotarget.26582
  7. Zhang, X., Qin, Y., Pan, Z., Li, M., Liu, X., Chen, X., … Li, D. (2019). Cannabidiol Induces Cell Cycle Arrest and Cell Apoptosis in Human Gastric Cancer SGC-7901 Cells. Biomolecules, 9(8), 302. doi:10.3390/biom9080302
  8. Straiker, A., Dvorakova, M., Zimmowitch, A., & Mackie, K. (2018). Cannabidiol Inhibits Endocannabinoid Signaling in Autaptic Hippocampal Neurons. Molecular pharmacology, 94(1), 743–748. doi:10.1124/mol.118.111864
  9. Thomas, A., Baillie, G. L., Phillips, A. M., Razdan, R. K., Ross, R. A., & Pertwee, R. G. (2007). Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro. British journal of pharmacology, 150(5), 613–623. doi:10.1038/sj.bjp.0707133
  10. Laprairie, R. B., Bagher, A. M., Kelly, M. E., & Denovan-Wright, E. M. (2015). Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor. British journal of pharmacology, 172(20), 4790–4805. doi:10.1111/bph.13250

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Applies To Full Spectrum Products

FDA Disclaimer: The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease. These products are not available for purchase to customers under the age of 18. All information presented here is not meant as a substitute for or alternative to information from healthcare practitioners. Please consult your healthcare professional about potential interactions or other possible complications before using any product. The Federal Food, Drug and Cosmetic Act requires this notice.

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