juices – Maven Bioscience

Posted on: August 30, 2022September 16, 2024

LATAM Conference in Panama 2022

Event Name: LATAM Conference in Panama 2022
Date: September 1 & 2, 2022

Maven Hemp is proud to be a gold sponsor for the 2022 LATAM CANN BIZ conference in Panama City, Panama.

LATAM CANN BIZ is an interdisciplinary conference focusing on global and regional industry trends and up-to-date information on emerging regulatory frameworks, technology, science, and best agricultural and production practices in the cannabis industry.

Maven Hemp’s CEO, Zev Barnett, will join over 40 other international speakers presenting talks sharing their insights and focusing on how to be successful in the cannabis industry.

Posted on: August 6, 2021June 12, 2024

Radicle Science Launches Study to Determine Effectiveness of CBD Products

Featuring Parker, Colorado-based CBD company Maven Hemp

The 3,000 participant study will capture and publish the most comprehensive data ever collected on CBD product effectiveness from 13 commercially available U.S. brands, including Maven Hemp.

Radicle Science, a transformative healthtech B-corp validating natural products for the first time, announces the launch of the Radicle ACES (Advancing CBD Education and Science) study.

Using a virtual, direct to consumer (D2C) approach, Radicle ACES is the largest and most comprehensive randomized controlled trial (RCT) of its kind, collecting data on thirteen mission-driven U.S. CBD brands, featuring Maven Hemp alongside ALTWELL, Charlotte’s Web, Columbia Care, Healer, Lord Jones, MD FARMA, Peels (a citrus-derived brand), Prospect Farms, PURAURA Naturals from Enhanced Botanicals, Rae Wellness, Trokie, and Verséa Wellness.

“We believe in the importance of having access to verified data that supports the ways our company makes a positive impact. Participating in the Radicle ACES study allows us to align with Radicle, a B-Corp that shares our values, while building trust and confidence as we work to distribute our products to doctors and patients across The Americas and beyond. We’re also in the process of B-Corp certification, and are making progress towards our impact goals every day. We’re proud to align with mission-driven partners, including Radicle Science and the other 12 brands in the Radicle ACES study.” – Zev Barnett, Founder and CEO of Maven Hemp

Radicle ACES is Institutional Review Board (IRB) approved and will capture CBD effectiveness data directly from 3,000 study participants. During the four-week study, participants will use the Radicle Science platform to track consumption and effectiveness of orally ingested CBD products on well-being, quality of life, pain, sleep disturbance, and anxiety.

Radicle ACES will use validated, standardized health indices to gather health outcome data from a diverse population across a variety of ethnicities, age groups, geographies, behavioral habits, and pre-existing health conditions.

“We’re applying science to understand the effectiveness of CBD products used by tens of millions of Americans every day,” said Jeff Chen, MD/MBA, Co-founder and CEO of Radicle Science.

Academic collaborators include Miroslav Backonja, MD (Clinical Professor, University of
Washington), Chris Colwell, PhD (Professor, UCLA), Derek Loewy, PhD (Director of Behavioral Sleep Medicine at Scripps Clinic Sleep Center), Ethan Russo, MD (Founder and CEO of CReDO Science), Kate Taylor, PhD (Associate Professor, UCLA), Jill Waalen, MD/MPH (Co-Director of Biostatistics at Scripps Research), and more.

The Real World Evidence (RWE) collected will inform scientific understanding on dosing, usage patterns, user characteristics, effectiveness across conditions, and predictors and modifiers of treatment response.

“The Radicle ACES study aims to answer lingering questions as to who should take cannabidiol, how much and for what conditions, as well as differing dosage patterns,” said Ethan Russo, MD, Scientific Expert for Radicle Science, and Founder and CEO of CReDO Science. “CBD is much more subtle in its effects and quite benign compared to THC. Patients are unclear on what product to choose and healthcare providers don’t yet have the data to counsel on proper dosage.”

For Maven Hemp, sharing data and answers from the Radicle ACES study will solidify the company’s ability to create positive impact across the local Colorado hemp production and consumption ecosystem. Alongside the company’s physician partners across the globe, as a custom product manufacturer, Maven Hemp aims to support the realization of improved patient outcomes.

Anonymized aggregate results will be released in October 2021. For more background on Radicle ACES methodology and additional insights from collaborators and experts involved in the study, see these Radicle Resources articles.

Follow Maven Hemp on LinkedIn and Instagram to stay updated on the Radicle ACES study as well as new product offerings. Visit the Maven Hemp website to browse through current products and engage with the company’s efforts to realize positive economic, social and environmental impact locally and internationally.

Posted on: November 10, 2019June 12, 2024

How do I Know CBD Oil is Safe?

CBD Compared to Other Drugs

There are many illegal drugs out there that can cause you harm if ingested in high doses. There are even legal, every day, food-borne drugs that must be consumed in moderation. Things like alcohol or nicotine can be lethal at high doses. Even caffeine can kill you if you drink too much of it. Cannabis oil, specifically CBD hemp oil, is actually much safer. In this article, we’ll talk about some of the reasons why.

CBD is Not Intoxicating

A group of doctors at the Mayo Clinic recently released a review of all the papers on the National Institute of Health regarding CBD oil. [1] The conclusion that they came to was that CBD and other hemp extracts were nonintoxicating and could have many potential uses in medicine. This review also looked at any adverse effects CBD might have on people.

Most Individuals can Tolerate Large Doses of CBD

Turns out, there were studies where people took high doses (300mg/day) for up to 6 months and were fine. Another showed that a group of patients took 4 to 5 times that dosage for 4 weeks and didn’t experience any bad side effects. With CBD, more is not always “more effective” with most people needing far less than any “maximum dose.” In fact, some recent data that we’ve collected, in concert with GoFire, reveals that consumers of Maven Hemp products find that maximum effectiveness is found in very moderate doses.

Favorably safe

One of the most attractive qualities of CBD is that even if you do experience side effects, they’re extremely mild compared to side effects from other drugs. A German study from 2017 found that cannabidiol was “favorably safe” for humans. The side effects included things like diarrhea, tiredness, and changes in appetite. [2] As with any drug, always discuss consuming CBD oil with your doctor if you are taking other drugs.

There was only one study where severe side effects were experienced, but even then, it was amongst psychiatric patients who were most likely taking other medication. Out of the 1600+ patients using CBD, only one person experienced severe side effects (muscle seizures and/or spasms). [3] Yes, you read that right, one out of over 1600+ patients.

CBD and Elevated Liver Function

A somewhat concerning observation came from some of these studies, though. Many of the patients had elevated liver function. This means that the liver is working overtime for some reason. Even the FDA suggests that patients get a liver function test before starting on the FDA-approved CBD drug, Epidiolex. [4]

Beware of Synthetic Cannabinoids

Based on these studies, natural CBD oil from the hemp plant is not harmful to people. However, synthetic cannabinoids have definitely killed people or left some with massive organ damage. [5] These synthetic chemicals have sketchy origins and are often laced with other things such as anticoagulants (these are chemicals that thin your blood and cause uncontrolled bleeding). [6]

The moral of the story is to make sure that you only purchase natural CBD oils. Always read the labels, ask questions, and check that the product has passed the Good Manufacturing Practice test. At Maven, all of our CBD products are tested for purity by independent third-party labs so you know what you’re putting in your body is the best quality, natural CBD in the country.

References

Vandolah, H. J., Bauer, B. A., & Mauck, K. F. (2019). Clinicians’ Guide to Cannabidiol and Hemp Oils. Mayo Clinic Proceedings, 94(9), 1840–1851. doi: 10.1016/j.mayocp.2019.01.003
Iffland, K., & Grotenhermen, F. (2017). An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies. Cannabis and cannabinoid research, 2(1), 139–154. doi:10.1089/can.2016.0034
Hoch, E., Niemann, D., von Keller, R., Schneider, M., Friemel, C. M., Preuss, U. W., … Pogarell, O. (2019). How effective and safe is medical cannabis as a treatment of mental disorders? A systematic review. European archives of psychiatry and clinical neuroscience, 269(1), 87–105. doi:10.1007/s00406-019-00984-4
Epidiolex [package insert]. Carlsbad, CA: Greenwich Biosciences, Inc; 2018. (US Food and Drug Administration website)https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210365lbl.pdf; 2018. (Published June 2018. Accessed November 16, 2018)
Spice/ K2, Synthetic Marijuana. (n.d.). Retrieved October 7, 2019, from https://www.dea.gov/factsheets/spice-k2-synthetic-marijuana.
National Institute on Drug Abuse. (2018, July 26). FDA Warns of Synthetic Cannabinoids Laced with Anticoagulant. Retrieved October 7, 2019, from https://www.drugabuse.gov/emerging-trends/fda-warns-synthetic-cannabinoids-laced-anticoagulant.

Posted on: November 8, 2019June 12, 2024

Cannabis, CBD, Hemp, THC, Marijuana – What’s the Difference?

There’s so much information out there about cannabis that it’s difficult to know what the difference is between all the terminology. However, when it comes to what products you put in, or on your body, either by inhalation, ingestion or application, it’s important to know what is what. In this post, we’ll take a look at the legal and/or scientific differences between some commonly used cannabis terms.

Cannabis

Cannabis (sometimes incorrectly referred to as “canibus oil” or “cannabus oil”) refers to a genus of plants. If you think back to biology class, you might remember that living organisms were divided into five kingdoms. Underneath each kingdom, the organisms were organized by phylum, class, order, family, genus, and species. Just like all dog-like creatures fall under the genus Canis, the genus Cannabis encompasses several types of plants that we just refer to as “cannabis” in everyday language. For the sake of clarity, the plant will be referred to as cannabis for the remainder of this article. [1]

Hemp vs Marijuana

Hemp refers to the species of cannabis plants that contain less than 0.3% THC. Marijuana refers to a species of cannabis plants that contain more than 0.3% THC. This distinction was made in the 2014 Farm Bill. [2] This legalized hemp on the federal level. In order for people to grow and sell hemp and hemp products, individual states had to legalize hemp on their own.

CBD vs THC

CBD and THC are both molecules that can be extracted from the cannabis plant. Depending on the strain of the plant, the levels of CBD and THC will vary. The main difference between these two molecules is that CBD is non-psychoactive and THC is psychoactive. Molecularly, they’re almost identical except for one part of the molecule where CBD has a hydroxyl group (-OH) hanging off of a carbon molecule while THC has a cyclic (closed) ring containing one oxygen molecule. This small difference completely changes the way CBD and THC interact with our endocannabinoid receptors. THC is able to bind to the receptors while CBD isn’t (has very low affinity). [3]

Why Terminology is Important

Cannabis terminology is important because when you’re out purchasing products, you’ll want to read labels, ingredients, and product descriptions. Depending on the state in which you live, there may be products available to you that are a mix of CBD and THC. Dispensaries in the 47 states where marijuana is legal will often market their products as either having some ratio of THC to CBD.

Marketing

Knowing the difference between these two cannabinoids can help you make better choices on what to buy. Plus, it’s impossible to avoid clever marketing and advertising. In an industry that is still quite new, some companies take liberties with their wording. Understanding cannabis terminology can help with avoiding some of these advertising tricks.

At Maven, all of our CBD products are clearly labeled with every ingredient and verified with third-party lab tests, so you know exactly what you are getting.

References

McPartland J. M. (2018). Cannabis Systematics at the Levels of Family, Genus, and Species. Cannabis and cannabinoid research, 3(1), 203–212. doi:10.1089/can.2018.0039
GovTrack.us. (2019). H.R. 2 — 115th Congress: Agriculture Improvement Act of 2018. Retrieved from https://www.govtrack.us/congress/bills/115/hr2
Atakan Z. (2012). Cannabis, a complex plant: different compounds and different effects on individuals. Therapeutic advances in psychopharmacology, 2(6), 241–254. doi:10.1177/2045125312457586